Publications
2020
Maha
Saber-Ayad,
Sarah
Hammoudeh,
Hadia
Radwan,
Shaista
Manzoor,
Hussein
Jabbar,
Rahaf
Wardeh,
Ahmed
Ashraf,
Peter
Habib,
Alsamman M.
Alsamman, and
Rifat
Hamoudi,
The FGF-21 genetic variants rs838133 and rs838145 are associated with high salt intake in the Emirati population, Journal of Advanced Research , vol. 24, pp. 485-494, 2020.
The FGF-21 genetic variants rs838133 and rs838145 are associated with high salt intake in the Emirati population, Journal of Advanced Research , vol. 24, pp. 485-494, 2020.
| DOI: | https://doi.org/10.1016/j.jare.2020.05.020 |
| File: | S209012322030103X |
2019
Maha
Saber-Ayad,
Shaista
Manzoor,
Hadia
Radwan,
Sarah
Hammoudeh,
Rahaf
Wardeh,
Ahmed
Ashraf,
Hussein
Jabbar, and
Rifat
Hamoudi,
The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population, PLOS ONE , vol. 14, Oct. 2019.
The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population, PLOS ONE , vol. 14, Oct. 2019.
| DOI: | 10.1371/journal.pone.0223808 |
Srinivasulu
Vunnam,
Monther
Khanfar,
Hany
Omar,
Raafat
ElAwady,
Scott
Sieburth,
Anusha
Sebastian,
Dana
Zaher,
Farah
Al-Marzooq,
Fatema
Hersi, and
Taleb
Al-Tel,
Sequencing [4+1]-Cycloaddition and Aza-Michael Addition Reactions: A Diastereoselective Cascade for the Rapid Access of Pyrido[2',1':2,3]/Thiazolo[2',3':2,3]imidazo[1,5-a]quinolone Scaffolds as Potential Antibacterial and Anticancer Motifs, The Journal of Organic Chemistry , vol. 2019, Oct. 2019.
Sequencing [4+1]-Cycloaddition and Aza-Michael Addition Reactions: A Diastereoselective Cascade for the Rapid Access of Pyrido[2',1':2,3]/Thiazolo[2',3':2,3]imidazo[1,5-a]quinolone Scaffolds as Potential Antibacterial and Anticancer Motifs, The Journal of Organic Chemistry , vol. 2019, Oct. 2019.
| DOI: | 10.1021/acs.joc.9b01919 |
Cijo
Vazhappilly,
Shabbir
Ansari,
Rula
Al-Jaleeli,
Aya
Al-Azawi,
Wafaa
Ramadan,
Varsha
Menon,
Rawad
Hodeify,
Shoib
Siddiqui,
Maxime
Merheb,
Rachel
Matar, and
Rajan
Radhakrishnan,
Role of flavonoids in thrombotic, cardiovascular, and inflammatory diseases, Inflammopharmacology , vol. 27, Oct. 2019.
Role of flavonoids in thrombotic, cardiovascular, and inflammatory diseases, Inflammopharmacology , vol. 27, Oct. 2019.
| DOI: | 10.1007/s10787-019-00612-6 |
Hayat
Jaibeji,
Debasmita
Mukhopadhyay,
Abdul khader
Mohammed,
Sarah
Dhaiban,
Mahmood
Hachim,
Noha
Elemam,
Nabil
Sulaiman,
Albert
Salehi, and
Jalal
Taneera,
Reduced Expression of PLCXD3 Associates With Disruption of Glucose Sensing and Insulin Signaling in Pancreatic β-Cells, Frontiers in Endocrinology , vol. 10, pp. 735, Oct. 2019.
Reduced Expression of PLCXD3 Associates With Disruption of Glucose Sensing and Insulin Signaling in Pancreatic β-Cells, Frontiers in Endocrinology , vol. 10, pp. 735, Oct. 2019.
| DOI: | 10.3389/fendo.2019.00735 |
Jalal
Taneera,
Sarah
Dhaiban,
Mahmood
Hachim,
Abdul khader
Mohammed,
Debasmita
Mukhopadhyay,
Khuloud
Bajbouj,
Rifat
Hamoudi,
Albert
Salehi,
Mawieh
Hamad, and
Affiliations,
Reduced Expression of Chl1 gene Impairs Insulin Secretion by Down-Regulating the Expression of Key Molecules of β-cell Function, Experimental and clinical endocrinology , pp. 1-9, 09 2019.
Reduced Expression of Chl1 gene Impairs Insulin Secretion by Down-Regulating the Expression of Key Molecules of β-cell Function, Experimental and clinical endocrinology , pp. 1-9, 09 2019.
| DOI: | 10.1055/a-1014-2544 |
Jalal
Taneera,
Israa
Mohamed,
Abdul khader
Mohammed,
Mahmood
Hachim,
Sarah
Dhaiban,
Abdullah
Malek,
Pontus
Dunér,
Noha
Elemam,
Nabil
Sulaiman,
Mawieh
Hamad, and
Albert
Salehi,
Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced β-cell dysfunction, Molecular and Cellular Endocrinology , vol. 499, pp. 110592, 09 2019.
Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced β-cell dysfunction, Molecular and Cellular Endocrinology , vol. 499, pp. 110592, 09 2019.
| DOI: | 10.1016/j.mce.2019.110592 |
Hany
Omar,
Ahmed
El-Serafi,
Fatema
Hersi,
El-Shaimaa
Arafa,
Dana
Zaher,
Mohamed
Madkour,
Hany
Arab, and
Mai
Tolba,
Immunomodulatory MicroRNAs in Cancer: Targeting Immune Checkpoints and the Tumor Microenvironment, FEBS Journal , 07 2019.
Immunomodulatory MicroRNAs in Cancer: Targeting Immune Checkpoints and the Tumor Microenvironment, FEBS Journal , 07 2019.
| DOI: | 10.1111/febs.15000 |
Sarah
Hammoudeh,
Arabella
Hammoudeh, and
Rifat
Hamoudi,
High-throughput quantification of the effect of DMSO on the viability of lung and breast cancer cells using an easy-to-use spectrophotometric trypan blue-based assay, Histochemistry and Cell Biology , vol. 152, 07 2019.
High-throughput quantification of the effect of DMSO on the viability of lung and breast cancer cells using an easy-to-use spectrophotometric trypan blue-based assay, Histochemistry and Cell Biology , vol. 152, 07 2019.
| DOI: | 10.1007/s00418-019-01775-7 |
Mohammed
El-Gamal,
Saif
Ullah,
Sayed
Zaraie,
Saquib
Jalil,
Sumera
Zaib,
Dana
Zaher,
Hany
Omar,
H.s
Anbar,
Julie
Pelletier,
Jean
Sévigny, and
Jamshed
Iqbal,
Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase, European Journal of Medicinal Chemistry , vol. 181, 07 2019.
Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase, European Journal of Medicinal Chemistry , vol. 181, 07 2019.
| DOI: | 10.1016/j.ejmech.2019.07.063 |
Jalal
Taneera,
Sarah
Dhaiban,
Abdul khader
Mohammed,
Debasmita
Mukhopadhyay,
Hayat
Jaibeji,
Nabil
Sulaiman,
João
Fadista, and
Albert
Salehi,
GNAS gene is an important regulator of insulin secretory capacity in pancreatic β-cells, Gene , vol. 715, pp. 144028, 07 2019.
GNAS gene is an important regulator of insulin secretory capacity in pancreatic β-cells, Gene , vol. 715, pp. 144028, 07 2019.
| DOI: | 10.1016/j.gene.2019.144028 |
Khaled
Abdellatif,
Wael
Fadaly,
Yaser
Mostafa,
Dana
Zaher, and
Hany
Omar,
Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities, Bioorganic Chemistry , vol. 91, pp. 103132, 07 2019.
Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities, Bioorganic Chemistry , vol. 91, pp. 103132, 07 2019.
| DOI: | 10.1016/j.bioorg.2019.103132 |
Cijo
Vazhappilly,
Ekram
Saleh,
Wafaa
Ramadan,
Varsha
Menon,
Aya
Al-Azawi,
Hamadeh
Tarazi,
Hajjaj
Abdu-allah,
Abdel-Nasser
El-Shorbagi, and
Raafat
el-awady,
Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types, Investigational New Drugs , vol. 37, pp. 1-10, 04 2019.
Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types, Investigational New Drugs , vol. 37, pp. 1-10, 04 2019.
| DOI: | 10.1007/s10637-018-0626-5 |
Jalal
Taneera,
Abdul khader
Mohammed,
Sarah
Dhaiban,
Mawieh
Hamad,
Rashmi
Prasad B,
Nabil
Sulaiman, and
Albert
Salehi,
RORB and RORC associate with human islet dysfunction and inhibit insulin secretion in INS-1 cells, Islets , vol. 11, pp. 1-11, 02 2019.
RORB and RORC associate with human islet dysfunction and inhibit insulin secretion in INS-1 cells, Islets , vol. 11, pp. 1-11, 02 2019.
| DOI: | 10.1080/19382014.2019.1566684 |
R.
{Hamoudi},
S.
{Hammoudeh},
A.
{Hammoudeh}, and
S.
{Rawat},
Semi-Automated Image Analysis Methodology to Investigate Intracellular Heterogeneity in Immunohistochemical Stained Sections, in 2019 IEEE International Conference on Imaging Systems and Techniques (IST) , 2019. pp. 1-4.
Semi-Automated Image Analysis Methodology to Investigate Intracellular Heterogeneity in Immunohistochemical Stained Sections, in 2019 IEEE International Conference on Imaging Systems and Techniques (IST) , 2019. pp. 1-4.
| DOI: | 10.1109/IST48021.2019.9010370 |
2018
Wafaa
Ramadan,
Cijo
Vazhappilly,
Ekram
Saleh,
Varsha
Menon,
Aya
AlAzawi,
Ahmed
El-Serafi,
Wael
Mansour, and
Raafat
el-awady,
Interplay between Epigenetics, Expression of Estrogen Receptor- α, HER2/ERBB2 and Sensitivity of Triple Negative Breast Cancer Cells to Hormonal Therapy, Cancers , vol. 11, pp. 13, Dec. 2018.
Interplay between Epigenetics, Expression of Estrogen Receptor- α, HER2/ERBB2 and Sensitivity of Triple Negative Breast Cancer Cells to Hormonal Therapy, Cancers , vol. 11, pp. 13, Dec. 2018.
| DOI: | 10.3390/cancers11010013 |
Ala'a
Al Hrout,
Amphun
Chaiboonchoe,
Basel
Khraiwesh,
Chandraprabha
Murali,
Badriya
Baig,
Raafat
el-awady,
Hamadeh
Tarazi,
Amnah
Alzahmi,
David
Nelson,
Yaser
Greish,
Wafaa
Ramadan,
Kourosh
Salehi-Ashtiani, and
Amr
Amin,
Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells, Scientific Reports , vol. 8, Nov. 2018.
Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells, Scientific Reports , vol. 8, Nov. 2018.
| DOI: | 10.1038/s41598-018-34855-0 |
Maha
Saber-Ayad,
Shaista
Manzoor,
Ahmed
El-Serafi,
Ibrahim
Mahmoud,
Sarah
Hammoudeh,
Aghila
Rani,
Salah
Abusnana, and
Nabil
Sulaiman,
The FTO rs9939609 “A” allele is associated with impaired fasting glucose and insulin resistance in Emirati population, Gene , Oct. 2018.
The FTO rs9939609 “A” allele is associated with impaired fasting glucose and insulin resistance in Emirati population, Gene , Oct. 2018.
| DOI: | 10.1016/j.gene.h.09.053 |
Jalal
Taneera,
Rashmi
Prasad B,
Sarah
Dhaiban,
Abdul khader
Mohammed,
Leena
Haataja,
Peter
Arvan,
Mawieh
Hamad,
Leif
Groop, and
Claes
Wollheim,
Silencing of the FTO gene inhibits insulin secretion: An in vitro study using GRINCH cells, Molecular and Cellular Endocrinology , vol. 472, 06 2018.
Silencing of the FTO gene inhibits insulin secretion: An in vitro study using GRINCH cells, Molecular and Cellular Endocrinology , vol. 472, 06 2018.
| DOI: | 10.1016/j.mce.2018.06.003 |
Cijo
Vazhappilly,
Shabbir
Ansari,
Vipin Shankar
Chelakkot,
Ayshwarya
Chelakkot,
Chaithanya
Lakshmi,
Varsha
Menon,
Wafaa
Ramadan,
Kannatt
Ethiraj,
Raafat
el-awady,
Theodora
Mantso,
Melina
Mitsiogianni,
Mihalis
Panayiotidis,
Graham
Dellaire, and
H P Vasantha
Rupasinghe,
DNA-dependent protein kinase: Epigenetic alterations and the role in genomic stability of cancer, Mutation Research/Reviews in Mutation Research , vol. 780, 06 2018.
DNA-dependent protein kinase: Epigenetic alterations and the role in genomic stability of cancer, Mutation Research/Reviews in Mutation Research , vol. 780, 06 2018.
| DOI: | 10.1016/j.mrrev.2018.06.001 |
Maha
Saber-Ayad,
Dana
Zaher,
Shaista
Manzoor, and
Hany
Omar,
PO-453 Effect of glp-1 on proliferation and migration in pheochromocytoma and colorectal cancer cells, 062018. pp. A199.3-A200.
PO-453 Effect of glp-1 on proliferation and migration in pheochromocytoma and colorectal cancer cells, 062018. pp. A199.3-A200.
| DOI: | 10.1136/esmoopen-2018-EACR25.475 |
Dana
Zaher, and
Hany
Omar,
95PEnergy restriction as a novel approach targeting breast cancer stem cells multi-drug resistance, Annals of Oncology , vol. 29, 03 2018.
95PEnergy restriction as a novel approach targeting breast cancer stem cells multi-drug resistance, Annals of Oncology , vol. 29, 03 2018.
| DOI: | 10.1093/annonc/mdy047.043 |
Jalal
Taneera,
Bashair
Mussa,
Maha
Saber-Ayad,
Sarah
Dhaiban,
Hayat
Jaibeji, and
Nabil
Sulaiman,
Maturity-Onset Diabetes of the Young: An Overview with Focus on the Middle East, Current Molecular Medicine , vol. 18, 02 2018.
Maturity-Onset Diabetes of the Young: An Overview with Focus on the Middle East, Current Molecular Medicine , vol. 18, 02 2018.
| DOI: | 10.2174/1566524018666180222121158 |
Shifaa
Abdin,
Dana
Zaher,
El-Shaimaa
Arafa, and
Hany
Omar,
Tackling Cancer Resistance by Immunotherapy: Updated Clinical Impact and Safety of PD-1/PD-L1 Inhibitors, Cancers , vol. 10, pp. 32, 01 2018.
Tackling Cancer Resistance by Immunotherapy: Updated Clinical Impact and Safety of PD-1/PD-L1 Inhibitors, Cancers , vol. 10, pp. 32, 01 2018.
| DOI: | 10.3390/cancers10020032 |
2017
Mony
Nader,
Shahd
Alotaibi,
Ebtehal
Alsolme,
Bariaa
Khalil,
Ahmed
Abu-Zaid,
Rahmah
Alsomali,
Dana
Bakheet, and
Nduna
Dzimiri,
Cardiac striatin interacts with caveolin-3 and calmodulin in a calcium sensitive manner and regulates cardiomyocyte spontaneous contraction rate, Canadian Journal of Physiology and Pharmacology , vol. 95, 08 2017.
Cardiac striatin interacts with caveolin-3 and calmodulin in a calcium sensitive manner and regulates cardiomyocyte spontaneous contraction rate, Canadian Journal of Physiology and Pharmacology , vol. 95, 08 2017.
| DOI: | 10.1139/cjpp-2017-0155 |
