Publications

2025

Faisal Alhosani, Reem Alhamini, Burcu Ice, Alaa Altaie, Nival Ali, Alaa Hamad, Axel Künstler, Cyrus Khandanpour, Hauke Busch, Basel Al-Ramadi, Kadria Sayed, Ali Alfazari, and Rifat Hamoudi,
Transcriptome-Wide Analysis and Experimental Validation from FFPE Tissue Identifies Stage-Specific Gene Expression Profiles Differentiating Adenoma, Carcinoma In-Situ and Adenocarcinoma in Colorectal Cancer Progression, International journal of molecular sciences , vol. 26, 2025.
DOI:https://doi.org/10.3390/ijms26094194
Baraa Al-Sheakly, Fatemeh Saheb Sharif-Askari, Narjes Saheb Sharif-Askari, Jennifer Hundt, and Rabih Halwani,
The potential role of nanobodies in asthma therapy, Frontiers in Pharmacology , vol. 15, 2025.
DOI:https://doi.org/10.3389/fphar.2024.1510806
Yasmina Lachine, Rania Hamdy, Salam Dakalbab, Imene K. Lazreg, Fatima Al Dhakeri, Sek Peng Chin, Najihah Mohd. Hashim, and Sameh S.M. Soliman,
Candida auris adhesins, specifically Als3, a key target to understand and mitigate, Mycologia , vol. 117, 2025.
DOI:https://doi.org/10.1080/00275514.2025.2536345
Rola AbuJabal, Tasneem Alanta, Reem Alhamini, Alaa Altaie, Lina Sahnoon, Bushra Mdkhana, Rifat Hamoudi, Bassam Mahboub , Yves Laumonnier, Khuloud Bajbouj, and Qutayba Hamid,
IL-5 signaling in asthmatic derived fibroblasts exacerbates airway remodeling through ECM dysregulation and apoptosis resistance, Respiratory Research , vol. 26, pp. 1–15, 2025.
DOI:https://doi.org/10.1186/s12931-025-03371-x
Baraa Al-Sheakly, Fatemeh Saheb Sharif-Askari, Narjes Saheb Sharif-Askari, Adel Zakir, Bushra Mdkhana, Mariam Eladham, Jennifer Hundt, Ibrahim Hachim, and Rabih Halwani,
Intranasal dupilumab improves responsiveness to steroid in an asthma mouse model, Inflammation Research , vol. 74, 2025.
DOI:https://doi.org/10.1007/s00011-024-01991-5

2024

Rola AbuJabal, Rakhee Ramakrishnan, Khuloud Bajbouj, and Qutayba Hamid,
Role of IL-5 in asthma and airway remodelling, Clinical & Experimental Allergy , vol. 54, pp. 538–549, 2024.
DOI:https://doi.org/10.1111/cea.14489
Faisal Alhosani, Burcu Ice, Reem Alhamini, Poorna Bhamidimarri, Alaa Hamad, Noura Alkhayyal, Axel Künstler, Cyrus Khandanpour, Hauke Busch, Basel Al-Ramadi, Kadria Sayed, Ali Alfazari, Riyad Bendardaf, and Rifat Hamoudi,
Transcriptome Profiling Associated with CARD11 Overexpression in Colorectal Cancer Implicates a Potential Role for Tumor Immune Microenvironment and Cancer Pathways Modulation via NF-κB, International Journal of Molecular Sciences , vol. 25, 2024.
DOI:https://doi.org/10.3390/ijms251910367
Ankita Srivastava, Rakhee Ramakrishnan, Rajan Radhakrishnan, Salah Abusnana, and Bashair Mussa,
Investigating the role of an immediate early gene FOS as a potential regulator of autophagic response to hypoglycemia in embryonic hypothalamic neurons, Clinical and Translational Science , vol. 17, 2024.
DOI:https://doi.org/10.1111/cts.13749Digital Object Identifier (DOI)
Lama Lozon, Wafaa S. Ramadan, Rawan R. Kawaf, Aya M. Al-Shihabi, and Raafat el-awady,
Decoding cell death signalling: Impact on the response of breast cancer cells to approved therapies, Life Sciences , vol. 342, pp. 122525, 2024.
DOI:https://doi.org/10.1016/j.lfs.2024.122525
File: S0024320524001140
Samah H. H. Ismail, Rania Hamdy, Alaa Altaie, Bahgat Fayed, Salam Dakalbab, Raafat el-awady, and Sameh S.M. Soliman,
Decoding host cell interaction– and fluconazole-induced metabolic alterations and drug resistance in Candida auris, Mycologia , vol. 116, 2024.
DOI:https://doi.org/10.1080/00275514.2024.2363730
Salam Dakalbab, Rania Hamdy, Patrícia Holigová, Eman Abuzaid, Ameera Abu-Qiyas, Yasmina Lachine, Mohammad.G. Mohammad, and Sameh S.M. Soliman,
Uniqueness of Candida auris cell wall in morphogenesis, virulence, resistance, and immune evasion, Microbiological Research , vol. 286, 2024.
DOI:https://doi.org/10.1016/j.micres.2024.127797

2023

Bariaa Khalil, Narjes Sharif-Askari, and Rabih Halwani,
Role of inflammasome in severe, steroid-resistant asthma, Current Research in Immunology , vol. 4, pp. 100061, 06 2023.
DOI:10.1016/j.crimmu.2023.100061
Alya R. Alnuaimi, Justus Bottner, Vidhya A. Nair, Nival Ali, Razaz Alnakhli, Eva Dreyer, Iman M. Talaat, Hauke Busch, Sven Perner, Jutta Kirfel, Rifat Hamoudi, and Wael M. Abdel-Rahman,
Immunohistochemical Expression Analysis of Caldesmon Isoforms in Colorectal Carcinoma Reveals Interesting Correlations with Tumor Characteristics, International Journal of Molecular Sciences , vol. 24, no. 3, 2023.
DOI:10.3390/ijms24032275

2022

Lama Lozon, Ekram Saleh, Varsha Menon, Wafaa Ramadan, Amr Amin, and Raafat el-awady,
Effect of safranal on the response of cancer cells to topoisomerase I inhibitors: Does sequence matter?, Frontiers in Pharmacology , vol. 13, 09 2022.
DOI:10.3389/fphar.2022.938471
Khuloud Bajbouj, Rola AbuJabal, Lina Sahnoon, Ronald Olivenstein, Bassam Mahboub , and Qutayba Hamid,
IL-5 receptor expression in lung fibroblasts: Potential role in airway remodeling in asthma, Allergy , vol. 78, pp. 882–885, 2022.
DOI:https://doi.org/10.1111/all.15627
Ankita Srivastava, and Bashair Mussa,
Effects of Varying Glucose Concentrations on ACE2′s Hypothalamic Expression and Its Potential Relation to COVID-19-Associated Neurological Dysfunction, International Journal of Molecular Sciences , vol. 23, 2022.
DOI:https://doi.org/10.3390/ijms23179645
Alya R Alnuaimi, Vidhya A Nair, Lara J Bou Malhab, Eman Abu-Gharbieh, Anu Vinod Ranade, Gianfranco Pintus, Mohamad Hamad, Hauke Busch, Jutta Kirfel, Rifat Hamoudi, and Wael M Abdel-Rahman,
Emerging role of caldesmon in cancer: A potential biomarker for colorectal cancer and other cancers, World journal of gastrointestinal oncology , vol. 14, no. 9, pp. 1637—1653, 2022.
DOI:10.4251/wjgo.v14.i9.1637
Bariaa A Khalil, Sarra B Shakartalla, Swati Goel, Bushra Madkhana, Rabih Halwani, Azzam A Maghazachi, Habiba Alsafar, Basem Al-Omari, and Mohammad T Al Bataineh,
Immune Profiling of COVID-19 in Correlation with SARS and MERS, Viruses , vol. 14, no. 1, pp. 164, 2022.
DOI:10.3390/v14010164
Wafaa Abumustafa, Batoul Abi Zamer, Bariaa A. Khalil, Mawieh Hamad, Azzam A. Maghazachi, and Jibran Sualeh Muhammad,
Protein arginine N-methyltransferase 5 in colorectal carcinoma: Insights into mechanisms of pathogenesis and therapeutic strategies, Biomedicine & Pharmacotherapy , vol. 145, pp. 112368, 2022.
DOI:https://doi.org/10.1016/j.biopha.2021.112368
File: S0753332221011525

2021

Wafaa Ramadan, Iman Talaat, Mahmood Hachim, Annette Lischka, Timo Gemoll, and Raafat el-awady,
The impact of CBP expression in estrogen receptor-positive breast cancer, Clinical Epigenetics , vol. 13, Dec. 2021.
DOI:10.1186/s13148-021-01060-2
Cijo Vazhappilly, Madumani Amararathna, Asha Cyril, Rebecca Linger, Rachel Matar, Maxime Merheb, Wafaa Ramadan, Rajan Radhakrishnan, and H P Vasantha Rupasinghe,
Current methodologies to refine bioavailability, delivery, and therapeutic efficacy of plant flavonoids in cancer treatment, The Journal of Nutritional Biochemistry , vol. 94, pp. 108623, 03 2021.
DOI:10.1016/j.jnutbio.2021.108623
Mahmood Hachim, Noha Elemam, Rakhee Ramakrishnan, Khuloud Bajbouj, Ronald Olivenstein, Ibrahim Hachim, Saba Al Heialy, Qutayba Hamid, Hauke Busch, and Rifat Hamoudi,
Wnt Signaling Is Deranged in Asthmatic Bronchial Epithelium and Fibroblasts, Frontiers in Cell and Developmental Biology , vol. 9, 03 2021.
DOI:10.3389/fcell.2021.641404
Sofia Rahman, Shimy Mathew, Pooja Nair, Wafaa Ramadan, and Cijo Vazhappilly,
Health benefits of cyanidin-3-glucoside as a potent modulator of Nrf2-mediated oxidative stress, Inflammopharmacology , pp. 1-17, 03 2021.
DOI:10.1007/s10787-021-00799-7
Sarah Dhaiban, Mena Ani, Noha Elemam, Mahmood Alaawad, Zeinab Al-Rawi, and Azzam Maghazachi,
Role of Peripheral Immune Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis, Sci , vol. 3, 02 2021.
DOI:10.3390/sci3010012